Nutrition, Sex, and Fetal Lung Maturation
نویسندگان
چکیده
منابع مشابه
Cited2 is required for fetal lung maturation.
Lung maturation at the terminal sac stage of lung development is characterized by a coordinated increase in terminal sac formation and vascular development in conjunction with the differentiation of alveolar type I and type II epithelial cells. The Cited2-Tcfap2a/c complex has been shown to activate transcription of Erbb3 and Pitx2c during mouse development. In this study, we show that E17.5 to...
متن کاملModeling glucocorticoid-mediated fetal lung maturation: II. Temporal patterns of gene expression in fetal rat lung.
Our previous report described the temporal steroid patterns during pharmacokinetic (PK) studies with dexamethasone (DEX) where doses of six 1 micromol/kg injections were given during gestational ages 18 to 20 days in rats. DEX PK was used in conjunction with the endogenous corticosterone profile to understand the regulation of fetal lung pharmacodynamics (PD). Expression of the glucocorticoid r...
متن کاملPre- and Postnatal Lung Development, Maturation, and Plasticity Effects of oligohydramnios on lung growth and maturation in the fetal rat
Kitterman, Joseph A., Cheryl J. Chapin, Jeff N. Vanderbilt, Nicolas F. M. Porta, Louis M. Scavo, Leland G. Dobbs, Robert Ertsey, and Jon Goerke. Effects of oligohydramnios on lung growth and maturation in the fetal rat. Am J Physiol Lung Cell Mol Physiol 282: L431–L439, 2002. First published October 5, 2001; 10.1152/ ajplung.00161.2001.—Oligohydramnios (OH) retards fetal lung growth by producin...
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Despite the evidence for early fetal experience exerting programming influences on later neurological development and health risk, very few prospective studies of human fetal behavior have been reported. In a prospective longitudinal study, fetal nervous system maturation was serially assessed by monitoring fetal heart rate (FHR) responses to vibroacoustic stimulation (VAS) in 191 maternal/feta...
متن کاملEndotoxin-induced maturation of monocytes in preterm fetal sheep lung.
The fetal lung normally contains immature monocytes and very few mature macrophages. The chorioamnionitis frequently associated with preterm birth induces monocyte influx into the fetal lung. Previous studies demonstrated that monocytes in the developing lung can mediate lung injury responses that resemble BPD in humans. We hypothesized that chorioamnionitis would induce maturation of immature ...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1974
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-197403000-00008